Terbinafine Hydrochloride EP Impurity F HCl CAS 926281-74-5 (free base)
| CAS No. | 926281-74-5 (free base) |
| Molecular Formula | C21H25N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 327.90 g/mol gives Terbinafine Hydrochloride EP Impurity F HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Terbinafine Hydrochloride EP Impurity F HCl (CAS 926281-74-5 (free base), C21H25NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Terbinafine Hydrochloride EP Impurity F HCl (C21H25NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 327.90 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Terbinafine Hydrochloride EP Impurity F HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H25N HCl |
| Molecular Weight | 327.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Terbinafine Standards
- Terbinafine Hydroxy Benzoate (CAS 1076198-30-5)
- Terbinafine Carboxylic Acid Methyl Ester (Oxalate) (CAS 1076199-76-2)
- Terbinafine Impurity 4 (Mixture of Z and E Isomers) (CAS 114311-70-5)
- Terbinafine Impurity 5-d7 (CAS 1185238-58-7)
- Terbinafine-d7 Hydrochloride (CAS 1185240-27-0)
- Terbinafine Impurity 4 (CAS 125660-64-2)
- Terbinafine Impurity 10 (CAS 126764-17-8)
- Terbinafine-d3 HCl (N-methyl-d3) (CAS 1310012-15-7)
Recommended Standards
- Metronidazole impurity 23 (CAS CATO-C4X-140523)
- Plerixafor impurity 38 (CAS CATO-C4X-113338)
- Peramivir Impurity 116 (CAS CATO-C4X-1833116)
- Mesulfen (CAS 135-58-0)
- 2-(2,6-Difluorophenyl)isonicotinic acid (CAS 1261930-34-0)
- N-(1-hydroxy-3-phenylpropan-2-yl)-4-iodobenzamide (CAS 478040-52-7)
- (S)-N-methyl-N-(piperidin-3-ylmethyl)methanesulfonamide (CAS 1558938-61-6)
- (2R,3R,4R,5R)-2-(2-Amino-6-(dimethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol (CAS 1336975-57-5)
- Cyclodeca[b]furan-4(5H)-one, 6,7,8,11-tetrahydro-3,6,10-trimethyl-, (E)- (CAS 88010-65-5)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com